TPC may refer to:
Organizations Tax Policy Center, for US tax analysis Technology Professionals Canada Texas Professional Communicators Trade Practices Commission, Australia Transaction Processing Performance Council, developing benchmark specifications for database systems Tropical Prediction Center, of the US National Hurricane Center TPC Group, a petrochemicals manufacturing company based in Houston, Texas, US Taiwan Police College, a police academy in Taiwan Taiwan Power Company The Pokémon Company Carabinieri Art Squad or (), a law enforcement division in Italy Turkish Petroleum Company, renamed Iraq Petroleum Company in 1925
Science and technology Table per Concrete Class, an inheritance strategy for Entity Framework Time projection chamber, a type of particle detector Thymolphthalein complexone, a chemical indicator Tough-pitch copper, a type of copper cable Trans Pacific Cable, a series of Pacific Ocean undersea cables Transmitter Power Control, for IEEE 802.11h-2003 WLAN Two-pore channel, an ion channel
Sports Tournament Players Championship, an earlier name of The Players Championship Tournament Players Championship (United Kingdom), a European Tour golf tournament TPC at Sawgrass, US golf course Tournament Players Club, a chain of golf courses
Transportation Air Calédonie (ICAO code) Parenzana (reporting mark), Trieste - Poreč - Kanfanar railway 1902–1935 Transports Publics du Chablais
Other uses Tokyo Police Club, an indie rock band from Canada The Perl Conference, now The Perl and Raku Conference Transitional Presidential Council, the interim head of state of Haiti