E60 or E 60 may refer to:

Transportation European route E60, a highway running from France to Kyrgyzstan BMW E60, a 2003–2010 platform number for the BMW 5 Series luxury German sedans GE E60, an American boxcab electric locomotive Mercedes-Benz E-60 AMG, in the Mercedes-Benz W124 series New Flyer E60, a high-floor trolleybus Obihiro-Hiroo Expressway, route E60 in Japan

Other uses Nokia E60, a mobile phone E:60, a sports television program on ESPN Electronika 60, a computer King's Indian Defence (Encyclopaedia of Chess Openings code)