Cals or CALS may refer to:
People with the surname Isabelle Cals, French opera singer Jo Cals (1914–1971), Dutch politician, Prime Minister of the Netherlands from 1965 to 1966 Adolphe-Félix Cals (1810–1880), French portrait and landscape painter
Organizations Central Arkansas Library System College of Agriculture and Life Sciences (disambiguation), a number of colleges at different universities
Technology Client access license, a Microsoft license technology Continuous Acquisition and Life-cycle Support, a United States Department of Defense initiative for electronically capturing military documentation and linking related information CALS Table Model, a standard for representing tables in SGML/XML CALS Raster file format, a standard for the interchange of graphics data