Michael Klein may refer to:

Michael Klein (art dealer) (born 1952), American artist’s agent and freelance consultant Michael Klein (businessman) (born 1951), Brazilian business executive Michael Klein (footballer, born 1959) (1959–93), Romanian football player with Corvinul Hunedoara and Romania , German football player with Eintracht Frankfurt Michael Klein (World Bank official) (born 1952), German banker Michael Klein (writer) (born 1954), American fiction writer, poet, and academic Michael L. Klein (born 1940), British-American computational chemist Michael R. Klein, American lawyer, co-founder of the Sunlight Foundation in 2006

See also Michael Clyne (1939–2010), Australian linguist, academic and intellectual Michael Klien (born 1973), Austrian choreographer and artist in Ireland Michel Klyne (1781–1868), Canadian employee of North West Company and Hudson's Bay Company