USS Charleston may refer to:
, a galley in commission from 1798 to 1802 , a protected cruiser commissioned in 1889 and wrecked in 1899 , a protected cruiser in commission from 1905 to 1923 , a gunboat in commission from 1936 to 1946 , an amphibious cargo ship in commission from 1968 to 1992 , a littoral combat ship commissioned on March 2, 2019 In fiction On the Beach (2000 film)