Donna J. Nelson (born 1954) is an American chemist and professor of chemistry at the University of Oklahoma. Nelson specializes in organic chemistry, which she both researches and teaches. Nelson served as the science advisor to the AMC television show Breaking Bad. She was the 2016 President of the American Chemical Society (ACS) with her presidential activities focusing on and guided by communities in chemistry. Nelson's research focused on six primary topics, generally categorized in two areas, Scientific Research and America's Scientific Readiness. Within Scientific Research, Nelson's topics have been on collecting, compiling, and disseminating CDC statistics revealing fentanyl death numbers and rates, on mechanistic patterns in alkene addition reactions, and on single-walled carbon nanotube (SWCNT) functionalization and analysis, yielding the first COSY NMR spectrum of covalently functionalized SWCNTs in solution. Under America's Scientific Readiness, she focuses on science education and impacting science by considering its communities; this includes classroom innovations and correcting organic chemistry textbook inaccuracies, on ethnic and gender diversity (the Nelson Diversity Surveys) among highly ranked science departments of research universities, and on improving the image and presentation of science and scientists to the public.Appearance on OCAST's science radio show,"Oklahoma Innovations" , Nov. 7, 2009Educational Television Association, Nov. 7, 2011, Norman, OK, aired Nov. 11, 2011.
Education and career Nelson was born in Eufaula, Oklahoma, a small town known as the center of the Muscogee Creek Nation. Her father was the only physician in the town. She earned her Bachelor of Science degree in chemistry at the University of Oklahoma. She obtained her PhD in chemistry at the University of Texas at Austin with Michael J. S. Dewar and did post-doctorate work at Purdue University with 1979 Chemistry Nobel Laureate Herbert C. Brown.Donna Nelson faculty page; University of Oklahoma; ; accessed May 23, 2013 Nelson joined the University of Oklahoma as a faculty member.
Nelson was a faculty fellow in the University of Oklahoma Provost's Office from 1989 to 1990. She was the first woman faculty fellow and the first assistant professor to enter the position, being promoted during the year. Anita Hill followed her, as the second female faculty fellow in the Provost's Office. Nelson was a visiting professor at the Massachusetts Institute of Technology in 2003 with Nancy Hopkins and in 2010 with Michael Strano.
In 2016, she served as president of the American Chemical Society.
Awards and honors
Nelson has received a number of honors and awards. These include American Chemical Society (ACS) President (2016), Fellow of the Royal Society of Chemistry (FRSC, 2019), an honorary doctorate from the University of Edinburgh (2021),url=https://www.dropbox.com/s/9udpyoaoijs1k0p/v2%20Donna%20Nelson%20-%20The%20University%20of%20Edinburgh.mp4?dl=0 Israel Chemical Society Fellow (2016), ACS Fellow (2010), ACS Henry Hill Award (for professionalism) (2013), Guggenheim Fellowship (2003), NSF Special Creativity Extension (1989),Nelson, Donna J. "Two-Year Extensions for Special Creativity" NSF Grant Proposal Guide, NSF 02-2, published December 2001 American Association for the Advancement of Science AAAS Fellow (2005), Sigma Xi Fellow (2020), Alpha Chi Sigma Hall of Fame (2022), National Organization for Women “Woman of Courage” Award (2004), Ford Foundation Fellowship (2003), Fulbright Scholarship (2007), and National Science Foundation (NSF) ADVANCE Leadership Award (2006). She was named one of the "70 Most Inspirational Women Leaders Impacting the World" by Business.org in 2018 and among "These 12 Texas Women Made History" by UT Austin in 2021.University of Texas at Austin, 2021 , She has also received the ACS Nalley Award (2011), ACS Stan Israel Award (2011), SACNAS Distinguished Scientist Award (2006), Oklahoma Higher Education Hall of Fame, (2013) ACS Oklahoma Chemist of the Year (2012), Oklahoma Outstanding Professor Award (2005), Women's eNews 21 Leaders for the 21st Century (2006), Minority Health Professions Foundation Hall of Fame Inductee (2005), and Sigma Xi Faculty Research Award (2001). In October 2017, FLOGEN Star Outreach awarded her with the Fray International Sustainability Award at SIPS 2017 (Sustainable Industrial Processing Summit), in Cancun, Mexico.
Nelson has written over 200 research-related publications, and has given hundreds of invited presentations to national meetings of professional societies and organizations, universities, and radio and TV programs, such as NPR, New York Times, Wall Street Journal, The NewsHour with Jim Lehrer and Marketplace Morning Report. The Journal of Organic Chemistry cover of February 4, 2005, and the ACS's Division of Organic Chemistry Calendar cover of September, 2006, each featured her research. The Chemical Heritage Foundation (2009), Society for the Advancement of Chicanos and Native Americans in Science (2004), and JustGarciaHill (2003) each collected her history to add to their collections of prominent scientist biographies. Nelson was made a member of the Daughters of the American Revolution in 2020, as a descendant of Thomas "Scotch Tom" Nelson and of Thomas Nelson Jr., a signer of the Declaration of Independence.
Scientific research
Addressing Fentanyl Poisonings Dr. Nelson collected, compiled, and disseminated CDC statistics showing that fentanyl deaths increased from 3,000 in 2013 to 75,000 in 2023. The dramatic increase in those 10 years convinced people that fentanyl is a serious problem in the US. She disaggregated annual death rates by race, gender and age, in order to determine which communities are being impacted most greatly. The highest death rates due to fentanyl are for Black males and Native American males, and these are still increasing, while other races are declining slightly. Fentanyl has become the major cause of death for Americans aged 18 through 45. For fiscal year 2023, US Border Patrol fentanyl seizures increased to 27024 lbs, which is 18 times the amount needed to kill every person in the US. She was alone in studying and reporting the statistics in these graphs. She also built a community doing bench chemistry on fentanyl, by organizing symposia on fentanyl at the 2023 Fall and 2025 Spring ACS Meetings and 2023 SWRM ACS Meeting. In her University of Oklahoma classes where she told students to carry Naloxone, her students thanked her, saying that they had lost friends or family members to fentanyl and that she was the only person at OU warning them about fentanyl.Nelson, Donna. "The US Fentanyl Challenge". https://academicminute.org/2024/08/donna-nelson-university-of-oklahoma-the-u-s-fentanyl-challenge/. August 13, 2024Nelson, Donna. "A Perfect Storm in Science". https://www.facebook.com/DrNealDunnFL2/videos/597486668900286 . February 27, 2023Nelson, Donna. "The Verdict". https://www.youtube.com/watch?v=5dI5frxgLpU. November 26, 2023Nelson, Donna. "The Fentanyl Crisis: It’s Worse Than You Think". www.news9.com/story/65c0fd8f1f99dc06565ee56c/the-fentanyl-crisis:-its-worse-than-you-think. February 4, 2024
Single-walled carbon nanotube (SWCNT) reactions In 2005, Nelson began applying to single-walled carbon nanotube (SWCNT) reactions the knowledge gained from her earlier research on the effects of substituents upon reactions of alkenes. She applied nuclear magnetic resonance spectroscopy (NMR) to examine the effects of substituents upon SWCNT reaction and association with a variety of classes of organic molecules, such as alcohols, amines, ketones, aldehydes and nitro compounds. By doing this, she pioneered the application of NMR to functionalized and pristine SWCNT characterization and analysis.Donna J. Nelson, Shagufta, and Ravi Kumar. “Characterization of a tamoxifen-tethered single-walled carbon nanotube conjugate by using NMR spectroscopy”. Anal. BioanalChem. 2012, 404, 771–776.Donna J. Nelson and Christopher N. Brammer. "Fluorine-Related Nanoscience with Energy Applications". ACS Symposium Series 1064, American Chemical Society. Washington, DC, 2011.Nelson, Donna J.; Brammer, Christopher N.; Nagarajan, Panneer S.; Perumal Paramasivan T. "Association of Representative Amides and Aminoalcohols with SWCNT as Revealed by NMR. Fluorine-related Nanoscience with Energy Applications". ACS Symposium Series 1064, American Chemical Society. Washington, DC, 2011, p. 31.Nelson, Donna J.; Murugesan, M.; Brammer, Christopher N.; Nagarajan, P. "Effects of NaHCO3 Washing and Change in Reagent Order upon the Reaction of Single-Walled Carbon Nanotubes with Thionyl Chloride and PMMA". Polymer Preprints., Am. Chem. Soc. 2010, 51 (1), 191.Nelson, Donna J.; Murugesan, M.; Brammer, Christopher N. "Effects of Sodium Bicarbonate Treatment on the Structure of Single-walled Carbon Nanotube Brands, Studied by Raman and Ultraviolet-Visible Spectroscopy". Polymer Preprints., Am. Chem. Soc. 2010, 51 (1), 577Nelson, Donna J.; Brammer, Christopher N.; Nagarajan, Panneer S.; Perumal, Paramasivan T. "Effect of Single-Walled Carbon Nanotube Association upon 1H NMR Spectra of Representative Organonitrogen Compounds". J. Phys. Chem". C 2010, 114, 10140-10147.Nelson, Donna J.; Brammer, Christopher N. "Pristine Single-Walled Carbon Nanotube Purity Evaluation by using 1H NMR Spectroscopy". Anal. Bioanal. Chem. 2009, 394, 1079-1086.Nelson, Donna J.; Perumal, Paramasivan T.; Brammer, Christopher N.; Nagarajan, Panneer S. "Effect of Single-Walled Carbon Nanotube Association upon Representative Amides". J. Phys. Chem. C 2009, 113, 17378–17386.Jaisankar, Sellamuthu N.; Nelson, Donna J.; Brammer, Christopher N. "New Synthesis and Characterization of Ionic Polyurethane-urea Liquid Crystals". J Polymer. 2009, 50, 4775-4780.Nelson, Donna J.; Strano, Michael. "Saving the world with nanotechnology". Nature Nanotechnology. 2006, 1, 96.
Reactions of alkenes As a physical organic chemist, Nelson developed a new synthetically useful technique for gathering mechanistic information on addition reactions of alkenes. The investigations often permitted selection of one mechanism from several which are proposed. The technique has helped determine mechanisms of important addition reactions of alkenes, such as hydroboration, oxymercuration, bromination, the Wacker process, and the Wilkinson's catalyst reaction.Soloshonok, Vadim; Nelson, Donna J. "Alkene Selenenylation: A Comprehensive Analysis of Relative Reactivities, Stereochemistry and Asymmetric Induction, and Their Comparisons with Sulfenylation".Beilstein J. Org. Chem. 2011, 7, 744-758. Nelson, Donna J.; Li, Ruibo; Brammer Christopher N. "Substituent Effects in Acid-Catalyzed Hydration of Alkenes, Measured Under Consistent Reaction Conditions". Tetrahedron Lett. 2009, 50, 6454-6456.Brammer, Christopher N.; Nelson, Donna J.; Li, Ruibo. "Substituent effects in additions of iodine thiocyanate to alkenes". Tetrahedron Lett. 2007, 48, 3237.Nelson, Donna J.; Li, Ruibo; Brammer, C. N. "Correlation of Relative Rates of Chromyl Chloride Oxidation and Chromic Acid Oxidation of Acyclic Alkenes Versus Alkene IPs and HOMOs". J. Phys. Org. Chem. 2004, 17, 1033 - 1038.