DRT may refer to:
Arts and entertainment DRT Entertainment, an American record label Drag Race Thailand, a Thai television show
Science Decimal reduction time, the period to kill 90% of microbes at a temperature Defense associated reverse transcriptase, a class of prokaryotic antiviral systems Discourse Representation Theory, in linguistics
Transport Del Rio International Airport, Texas, United States (IATA code) Demand-responsive transport, a form of public bus service Downtown Relief Line, a proposed subway line in Toronto, Canada Durham Region Transit, a Canadian public transit operator Digital-rail Rapid Transit, a type of Autonomous Rail Rapid Transit
Other uses Daughters of the Republic of Texas, a lineage society Dismounted reconnaissance troop, a type of U.S. Army formation Doña Remedios Trinidad, Bulacan, a municipality in the Philippines