GBU may refer to:
Organizations Air Bissau (ICAO code: GBU), the national airline of Guinea-Bissau Football Association of Greenland (Grønlands Boldspil-Union), the governing body of association football in the island country of Greenland Gabriel Resources (TSX-V code: GBU), a Canadian resource company Gaston Berger University, the second university established in Senegal Gautam Buddha University, a university established by the Uttar Pradesh Gautam Buddha University Act 2002 Groupes Bibliques Universitaires, student groups that meet at universities or nearby for in-depth Bible study
Precision-guided munitions "Guided Bomb Unit" GBU-10 Paveway II, an American Paveway-series laser-guided bomb GBU-12 Paveway II, an American aerial laser-guided bomb GBU-15, an unpowered, glide weapon GBU-16 Paveway II, an American Paveway-series laser-guided bomb GBU-24 Paveway III, a family of laser-guided bombs GBU-28, a 5,000-pound laser-guided "bunker busting" bomb GBU-27 Paveway III, a laser-guided bomb with bunker buster capabilities GBU-37 GPS-Aided Munition, a GPS-Aided Munition developed for use with the B-2 Bomber GBU-39 Small Diameter Bomb, a 250 lb precision-guided glide bomb GBU-43/B MOAB, a large-yield bomb GBU-44/B Viper Strike, a GPS-aided laser-guided variant of the Northrop Grumman Brilliant Anti-Tank munition GBU-53/B, an American air-launched, precision-guided glide bomb GBU-57A/B MOP,a 30,000-pound (13,600 kg)-class precision-guided "bunker buster" bomb developed for the United States Air Force (USAF)
Other The Good, the Bad and the Ugly - 1966 Spaghetti western film Good Bad Ugly - 2025 Indian film Countermine System (also GBU-61), an anti-land-mine system consisting of chemical or explosive projectiles Gaagudju language (ISO 639-3 code: gbu), an extinct Australian Aboriginal language GBU Indoor Stadium, an indoor stadium located in the campus of Gautam Buddha University