Rubini is a surname of Italian origin. Notable people with the surname include:
Cesare Rubini, Italian basketball player Gabriele Rubini, Italian television presenter Giambattista Rubini, Italian Catholic cardinal Giovanni Battista Rubini, Italian tenor Giulia Rubini, Italian actress Jan Rubini, Swedish-American violinist and conductor Michel Rubini, American musician and composer (son of Jan Rubini) Olinto Sampaio Rubini, Brazilian footballer Sergio Rubini, Italian actor and film director
See also Rubini (song), 2021 song by Mahmood and Elisa Rupini Nouriel Roubini