Charles Brandon may refer to:

Charles Brandon, 1st Duke of Suffolk (1484–1545), close friend and brother-in-law of Henry VIII Charles Brandon, 3rd Duke of Suffolk (1537–1551), second son of the above and his fourth wife, Catherine Willoughby Charles Brandon (died 1551), MP, illegitimate son of 1st Duke of Suffolk Charles Brandon (The Tudors)

See also Charlie Brandon (1943–2022), Canadian football player