Rusticus is a Latin adjective meaning "rural, simple, rough or clownish" and can refer to:

Animals a synonym of the butterfly genus Plebejus

People Saints and martyrs Saint Rusticus of Narbonne (died c. 461) Saint Rusticus (Archbishop of Lyon) (c. 455–501) One of the martyred companions of Saint Denis (3rd century) Martyr of Verona (died c. 290): see Firmus and Rusticus

Other people Fabius Rusticus, 1st-century historian of ancient Rome Arulenus Rusticus, (c. 35–93 AD) consul executed by Domitian Flavius Rusticus Helpidius, 5th-century Latin poet Junius Rusticus, 2nd-century Stoic philosopher, consul, and friend of Marcus Aurelius