Ghosn is a surname. Notable people with the surname include:
Carlos Ghosn (born 1954), businessman and automotive executive Caroline Ghosn (born 1987), American businesswoman Fadi Ghosn (born 1979), Lebanese footballer Fayez Ghosn (1950–2021), Lebanese politician Maguy Bou Ghosn (born 1977), Lebanese actress Jad Ghosn (born 1986), Lebanese journalist Nicolas Ghosn (1940–2018), Lebanese politician and lawyer Tiki Ghosn (born 1977), Lebanese-born American mixed martial artist