Lipuš or Lipus is a Slovene-language surname. Notable people with the surname include:

Cvetka Lipuš (born 1966), Austrian poet writing in Slovenian Florjan Lipuš (born 1937), Carinthian Slovene writer (born 1965), Austrian (Carinthian Slovene) singer, singing teacher and composer (1893–1961), German artist See also

Low intensity pulsed ultrasound (LIPUS), a medical technology