James MacNeill is the name of:
James A. MacNeill (1854–1927), former merchant and politician from Prince Edward Island, Canada James McNeill (1869–1938), Irish politician and diplomat James Walter MacNeill (1873–1945), first superintendent of Saskatchewan Hospital, North Battleford, Saskatchewan Jim MacNeill (1928–2016), Canadian consultant, environmentalist, and international public servant
See also Jim McNeil (1935–1982), Australian playwright Jim McNeill, Polar Explorer