Mean Machine may refer to:

Music Mean Machine (Lucifer's Friend album) Mean Machine (U.D.O. album) Mean Machine (band), a Japanese rock band The Mean Machine (rap group) "Mean Machine", a song by The Last Poets on the album This Is Madness "Mean Machine", a song by Sugar Ray on the album Lemonade and Brownies "Mean Machine", a song by Motörhead on the album Orgasmatron The Mean Machine (album), an album by Jimmy McGriff

Sport Mean Machine (sailing team) Roy Shaw (1936–2012), British boxer Mean Machine RFC, a rugby club in the Kenya Rugby Football Union Football teams in The Longest Yard, and its 2005 remake A 1982 Commonwealth Games relay team including Graeme Brewer, Neil Brooks, Greg Fasala, and Michael Delany

Other uses Mean Machine (film), a 2001 British sports comedy film Mean Machine Angel, a character in the Judge Dredd universe "Mean Machine," a Hi Hi Puffy AmiYumi episode The Mean Machine, Dick Dastardly's car in the TV series Wacky Races