Luppi is a surname, and may refer to:
Daniele Luppi (born 1972), Italian musician Davide Luppi (born 1990), Italian footballer Ermenegildo Luppi (1877–1937), Italian sculptor Federico Luppi (1936–2017), Argentine actor Jacopo Luppi (born 1992), Italian footballer Luppi (Bleach), a fictional character in Bleach Michele Luppi (born 1974), Italian singer and keyboardist