Notable people named Rudolf Holzapfel include:

Rudolf Maria Holzapfel (1874–1930), a Polish-Austrian psychologist and philosopher Rudolf Melander Holzapfel (1900–1982), a Shakespeareean scholar and art dealer Rudi Holzapfel (1938–2005), an Irish poet and teacher; son of Rudolf Melander

See also Holzapfel Rudolph (name)