D500 may refer to:
Dodge D500, a variant of the Chrysler B engine D500 road (Croatia) Dewoitine D.500, an aircraft Dodge D-500 (disambiguation), a performance model automobile Durrum D-500, an amino acid analyser Nikon D500, a 20.9 megapixel DSLR camera Samsung SGH-D500, a mobile phone Dell Latitude D500, a laptop