Sanguine may refer to:

Sanguine (red chalk), a red pigment used in art Sanguine temperament, a personality type, one of the four temperaments Blood red, a dark shade meant to resemble the color of human blood Sanguine (heraldry), a tincture of a blood-red color Sanguine, a fruit, type of blood orange HMS Sanguine, a submarine built for the Royal Navy in 1945 Project Sanguine, a 1968 US Navy research project for radio communication with submarines Sanguine (band), a British alt-metal band formed in 2004

See also Sanguin (disambiguation) Sanguino