DPO may refer to:
Economics Data protection officer, under European corporate regulation Days payables outstanding, in finance Detrended price oscillator, indicator in financial technical analysis Direct public offering, method by which a business can offer an investment opportunity to the public
Entertainment "D.P.O." (The X-Files), 1995 television episode Dayton Philharmonic Orchestra Dublin Philharmonic Orchestra
Science and technology Digital Phosphor Oscilloscope, a type of electronic test instrument Direct preference optimization, a technique for aligning AI models with human preferences Double pushout graph rewriting, in computer science
Other Dame of the Pontifical Order of Pius IX, rank of the honorific order Democratic Party of Oregon United Nations Department of Peace Operations, overseeing UN peacekeeping operations Devonport Airport, IATA code Discontinued post office Diplomatic Post Office, system providing postal services to diplomatic missions of the United States Digital Policy Office, Hong Kong government agency