Millstream may refer to:

Places Australia Millstream, Queensland, locality in the Tablelands Region, Queensland Millstream, a headstream of the Herbert River, Queensland Millstream Falls, Queensland Millstream-Chichester National Park, national park in Western Australia Millstream Station, former pastoral lease in Western Australia

Other Millstream Brewing, a small beer brewery located in Amana, Iowa.

The Millstream, a fictional stream in the World of Greyhawk campaign setting for the Dungeons & Dragons role-playing game.

A leat, an artificial watercourse or aqueduct dug into the ground, supplying water to a watermill or its mill pond

See also Mill Stream (disambiguation), similarly named places or objects